Week 2 delivers an early-season showdown with playoff implications as the Denver Broncos storm into Lucas Oil Stadium to face the Indianapolis Colts in a Sunday afternoon clash (4:05 PM ET). Both teams enter this matchup hungry to prove their Week 1 performances were no fluke—Denver looking to build on their momentum, while Indianapolis aims to silence doubters on home turf. The Broncos' high-octane offense will test a Colts defense that prides itself on discipline, setting up a chess match between schemers and playmakers.

With the NFL landscape still taking shape, this game could serve as a measuring stick for two franchises with Super Bowl aspirations. The Colts' home-field advantage and the Broncos' road-tested resilience create a volatile mix, ensuring every snap will carry weight. Can Denver's explosive weapons outpace Indianapolis' methodical attack? Or will the Colts' defense rise to the occasion in primetime? Sunday's answer will echo through the season.